The Followers Safehouse and Griffin Wares Sacked Caravan are to the north of Vault 22, Silver Peak Mine is to the west, and Ranger Station Foxtrot is to the south. There are locations you could possibly quick-travel to that would get you there quicker, however. Vault 22 is located due east (quite a distance) from Jacobstown. Vault 22 is located in an overgrown, flowery, lush grove at the northwestern edge of the Mojave Wasteland. The final location you have to visit is Vault 22.
